1993 Volume 46 Issue 11 Pages 1638-1642
Thiazohalostatin is a new cytoprotective substance produced by Actinomadura sp. HQ24. Its structure was elucidated as shown in Fig. 1 by NMR spectral analyses and chemical modifications. Thiazohalostatin was found to possess a novel skeleton containing trichloropyrrole and thiazoline ring moieties.