Quinolactacins A, B and C: Novel Quinolone Compounds from Penidllium sp. EPF-6

II. Physico-chemical Properties and Structure Elucidation

抄録

Three novel quinolone compounds, quinolactacins A (1), B (2) and C (3), Have been found from the fermentation broth of Penidllium sp. EPF-6, a fungus isolated from the larvae of mulberry pyralid (Margaronia pyloalis Welker). The molecular formulas of 1, 2 and 3 were determined to be C₁₆H₁₈N₂O₂, C₁₅H₁₆N₂O₂ and C₁₆H₁₈N₂O₃, respectively by FAB-MS and NMR spectral analyses. The structures of these compounds have a novel quinolone skeleton with a γ-lactam ring consisting of C₁₂H₈N₂O₂ as the common chromophore.