The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
IB-96212, a Novel Cytotoxic Macrolide Produced by a Marine Micromonospora
II. Physico-chemical Properties and Structure Determination
LIBRADA M. CAÑEDOJOSÉ L. FERNÁNDEZ PUENTESJULIA PÉREZ BAZX-H. HUANGK. L. RINEHART
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2000 年 53 巻 5 号 p. 479-483

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IB-96212, is a new member of spiroketal containing macrolide class of fermentationderived natural products isolated from mycelial extracts of Micromonospora sp. The structure consists of a new aglycone which possesses a 26-membered macrolide ring system and of one deoxy sugar identified as L-rhodinose, this structure represents the first reported spiroketal macrolide natural product related to other macrolides, such as oligomycins, dunaimycins, citovaricin, rutamycin and ossamycin.
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© Japan Antibiotics Research Association
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