New Triene-ansamycins, Thiazinotrienomycins F and G and a Diene-ansamycin, Benzoxazomycin

抄録

New triene-ansamycins designated thiazinotrienomycins F (TT-F) and G (TT-G) and a new diene-ansamycin, benzoxazomycin, were isolated from a culture broth of Streptomyces sp. MJ672-m3 and their structures were elucidated by spectroscopic analyses. The Mean Graphs of TT-G suggests that the tumor growth inhibitory activities are almost as strong as TT-B, in respect of GI₅₀ and TGI against several human cancer cell lines.