Kigamicins, Novel Antitumor Antibiotics
II. Structure Determination
2003 年 56 巻 12 号 p. 1012-1017
詳細
2003 年 56 巻 12 号 p. 1012-1017
Kigamicin A (1), B (2), C (3), D (4) and E (5) are novel antitumor antibiotics. Their structures were determined by spectroscopic analyses including various NMR measurements. Kigamicins have a unique aglycone of fused octacyclic ring system containing seven of sixmembered rings and one oxazolidine. The aglycone links a sugar chain composed of one to four deoxysugars. These sugars were found to be amicetose and oleandrose.
