The Japanese Journal of Antibiotics
Online ISSN : 2186-5477
Print ISSN : 0368-2781
ISSN-L : 0368-2781
CLINICAL STUDY OF CS-1170 IN CHILDREN
KAZUAKI NAGAMATSUISAMU HAMADA
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1979 Volume 32 Issue 2 Pages 238-240

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Abstract
CS-1170 was administered to 9 cases of the pediatric field. The clinical effect was good in 6 cases, fair in 2, and poor in one. The doses ranged from 80 mg/kg to 100 mg/kg, and an intravenous injection of 300 mg/kg was given in only one case.
In the poor case, continuous instillation of 100 mg/kg was given. In the 2 fair cases, the patients with septicemia received 80 mg/kg and 300 mg/kg, respectively. There was no improvement in clinical findings, but the bacteria alone disappeared.
As side effects, vasalgia due to intravenous injection was observed in 2 cases, but it disappeared by the intravenous injection of 500 mg dissolved in 10 ml. No case showed eruption, diarrhea, or acidophilia. GOT or GPT increased in no case either.
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© Japan Antibiotics Research Association
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