CLINICAL STUDIES OF9, 3-DIACETYLMIDECAMYCIN IN PEDIATRIC FIELD
1982 Volume 35 Issue 2 Pages 421-428
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1982 Volume 35 Issue 2 Pages 421-428
Clinical trials of9, 3-diacetylmidecamycin (MOM), a new macrolide antibiotic were carried out on 46 pediatric patients of 1 month to 11 years old with infections (acute pharyngitis12, acute tonsillitis 1, acute bronchitis14, asthmatic bronchitis10, acute pneumonia 1, primary atypical pneumonia2, Mycoplasma pneumonia 4 and pertussis2).As a rule, MOM was given orally at a daily dose of20-40mg/ kg divided into 3 times.The clinical results were excellent in 5patients, good in 21, fair in 7 and poor in 13 and the efficacy rate was 56.5%.Side effects were observed in 4 patients (diarrhea, exanthema, urticaria and eosinophilia, 1patient respectively).
MOM is easy to take and a useful antibiotic for treating pediatric patients with bacterial infections, in particular, respiratory tract infection caused by Mycoplasma pneumoniae.
