Studies on Stabilization of Variotin

抄録

Variotin is a new antifungal antibiotic discovered by Yonehara, Takeuchi and others^1,2,3). It is a neutral oily substance, produced by Paecilomyces varioti Bainier var. antibioticus.

Notwithstanding its strong activity against pathogenic fungi such as Trichophyton and Blastomyces, industrial production of variotin has been difficult because of low stability. In the studies on stabilization of variotin preparations, following results were obtained.