Pathocidin, A New Antifungal Antibiotic. I Isolation, Physical and Chemical Properties, and Biological Activities

抄録

In the course of searching for new antibiotic effective against pathogenic fungi, the culture broth of a streptomycete showed high activities against Piricularia oryzae, etc., and two antifungal substances were isolated in crystalline forms. One of them was proved to be identical with blasticidin S by comparing ultraviolet and infrared absorption spectra and other properties, but another one was found to be a new antibiotic and named as pathocidin. In this report, its isolation and purification, physical and chemical properties as well as antibiotic activities are described. The taxonomic study of the strain will be reported later.