Gougerotin, A New Antibacterial Antibiotic

Abstract

In the course of screening tests, searching for new antibiotics, a strain, Streptomyces sp. No. 21544, which was isolated from a soil sample collected in Kyoto City, was found to produce a new antibiotic active against various bacteria including Gram-positive, Gram-negative and mycobacteria.

The antibiotic isolated from this strain has a broad expectrum against bacteria but weak antibiotic activity. This antibiotic was compared with known antibiotics on the basis of biological chemical and physical properties, and found to be a new antibiotic. Therefore, this antibiotic was named gougerotin.