唾液腺摘出が胃粘膜に及ぼす影響に関する化学的, 組織学的研究
II. 胃粘膜の細胞学的觀察
1956 年 11 巻 1 号 p. 57-64
詳細
1956 年 11 巻 1 号 p. 57-64
The author fed rats 1, 5, 10, 20 and 30 days after the total extirpation of the parotis gland or the parotis, submandibular and sublingual glands, then observed the peptic cells, the parietal cells and the surface-cells of the mucosa of the stomach.
In the peptic cells the vigorous production of secretion granules continued after the diet-administration only in the case of the day after the operation. In other cases the cell function was so irregular that the significance of which could not be understood, on the other hand the degenerated cells were often recognizable. The parietal cells were relatively balanced in their secretory functional images, but their functional movement after the diet-administration was irregular and its significance was hardly understood as well as in the peptic cells. On the other hand the functional unbalance could be seen often.
From the fluctuation of the productin vacuoles (FUJIE) contained in the surface-cells of the gastric mucosa, the author could presume a continuous but grade-irregular secretion of productin (gastric hormone proposed by FUJIE to be called so). However it was not so vigorous as to be presumed from the histamine value in the blood. The author considered that the incomplete treatment of productin (histamine-like) which was secreted from the gastric mucosa into blood, owing to the deficience of the salivary glands, has brought about the high value of histamine in the blood.
