顎下腺と舌下腺摘出が耳下腺細胞分泌機能及び血中ヒスタミンに及ぼす影響

抄録

The author, who has previously studied the submandibular gland cells of rats from which the parotis gland were extirpated, has here studied the parotid gland cells after the chirurgical extirpation of the submandibular and sublingual glands and compared the results with those obtained in former experiment. The results common to both experiments were 1. secretion vacuoles in the cells did not decrease even after administration of the diet, the gland lumen and the intercalary duct dilated for a long period after the diet administration, and the secretory function, production and discharge of the secretory substance, was most likely promoted, 2. nuclei of the cells increased their size. The main points of difference were 1. nuclei of the parotid gland cells after the extirpation of the submandibular and sublingual glands increased their stainability, and a marked increase of nucleic acid were recognizable, but the nuclei of the submandibular gland cells after the extirpation of the parotis gland, were not so, 2. histamine in the blood increased abnormally in the case of the extirpation of the parotis gland, however it decreased and was lower than normal in the case of the extirpation of the submandibular and sublingual glands.
As a result of these studies, it is presumed that the composition of the secretory substance of the cells of the parotid and of the submandibular glands may be different, though the cells of both glands are similar serous cells and the secretory function of these glands has been promoted to same extent, and that the compositional difference is apparent by reason of the anti-histamic action (FUJIE) etc.