抄録
In this paper we have studied cytologically the eosinophil cells in the mucous membrane of the human gastrointestinal tract. Materials were obtained from 5 healthy executed men and 21 appendices resected at gynecological operations.
The eosinophil cells are distributed chiefly in the lamina propria of the mucous membrane and are especially numerous in its deep parts near the lamina muscularis mucosae. Generally they gradually increase in number as we descend to the distal portions of the intestine. In the tela submucosa, however, usually none of them are found except in the superficial parts near the above mentioned muscle layer.
The majority of them have either a compact round nucleus or a two-lobed one. In the cytoplasm, we find occasionally among the eosinophil granules several rod-like and minute spherical inclusions which appear to represent the mitochondria of these cells: we could not, however, distinguish them according to staining and fixation properties from eosinophil granules.
The structure of the GOLGI apparatus of the eosinophil cells are very simple, consisting always of a single C-shaped strand. The characteristic structure of the GOLGI apparatus as seen in the eosinophil myelocytes of the bone marrow is never recognized in the eosinophil cells of the mucous membrane. This fact indicates that they are not myelocytes but more likely eosinophil leucocytes.
Furthermore we often find pictures which reveal the migration of the eosinophil cells from the blood vessels into the connective tissue. The mitosis of these cells were not observed.
From above mentioned facts we came to the conclusion that the eosinophil cells found in the mucous membrane of the gastrointestinal tract are nothing but the eosinophil leucocytes migrated from blood vessels into the connective tissue.
