抄録
The total excision of the dog's pancreas was performed, then the author observed the cells of the parotid gland from the 1st day to the 8th day after the operation.
In the gland cells, the secretory function seems somewhat abnormal after the opertion, and in the 6th day the remarkable change appears, then the basal portion of the cell is occupied by the giant vacuoles.
In the epithelial cells of the secretory duct, the structure is quitely normal till the 4th day, but in the 5th day plastosomes in the basal portion of the cell show some tendency to trausform into giant granules and in the 6th day the big vacuoles appear in the subnuclear portion.
Then, in both the gland cell and the epithelial cell of the secretory duct the giant vacuoles appear in the basal portion on the 6th day after the operation. These vacuoles increase, fuse together and make a lucid zone.
Such changes as above mentioned are quite identical with the ones which are recognized in the parotid gland of the alloxan-diabetes rabbits. Therefore it is believed that the giant vacuo es have a relationship with diabetes and they can be important proof for the endocrine secretion theory of the parotid gland.
