抄録
The author studied the influence of brain ischemia on ABR, the author used Mongolian gerbils which have an insufficient Willis'brain circulation.
At first, the right cochlea was destructed but the left auditory pathway was kept intact. The right common carotid artery (CA) was ligated to produce ischemia of the right brain hemisphere.
The unilateral auditory pathway was confirmed by the evoked potentials of the inferior colliculus. The unilateral brain ischemia was determined by the abnormal movement, dyeing (2% Evans blue) of brain artery, and pathological specimens.
Finally, the ABR of 8 animals was recorded successively from the ligation of the right CA to death. During 3 hours of ischemia, III-V waves of ABR were slightly delayed, but the total pattern of ABR did not change greatly. After 10 hours the I wave remained and the other waves disappeared. The change of ABR seemed not directly influenced by brain ischemia, but inffluenced by the increased intracranial pressure due to brain edema.
