Relation between Isolated Venous Thrombi in Soleal Muscle and Positive Anti-Nuclear Antibody

Abstract

Objective: In patients with isolated soleal vein thrombosis (SVT), the relation between acute thrombi and positive anti-nuclear antibody (ANA) was investigated.
Subjects and Methods: The subjects were 116 lower extremities in 86 patients with SVT. They were diagnosed and examined by ultrasonography and blood serum analysis (D-dimer, ANA), and had been followed up every three months.
Results: They had acute SVT in 35 limbs (30%) and chronic SVT in 86 limbs (70%), and they had positive ANA in 63%. They had recurrent SVT in 26%, and all were positive for ANA.
Conclusion: ANA-positivity might be a risk factor for acute thrombi in patients with SVT. (English Translation of J Jpn Coll Angiol 2010; 50: 417-422.)