Comparison of Precursor Structures of the GGNG Peptides Derived from the Earthworm Eisenia foetida and the Leech Hirudo nipponia

Abstract

  Earthworm and leech cDNAs encoding the GGNG peptides, a family of myotropic peptides, were cloned and examined in this study. Both of the predicted precursor proteins are of polyprotein structure and contain several putative peptides distinct from the GGNG peptides. However, the precursors show organizations distinct from each other and no sequence similarity except for the GGNG peptides.