Effect of a Polysaccharide (TAP) from the Fruiting Bodies of Tremella aurantia on Glucose Metabolism in Mouse Liver

Tadashi KIHO; Hotaka MORIMOTO; Takashi KOBAYASHI; Shigeyuki USUI; Shigeo UKAI; Koichi AIZAWA; Takahiro INAKUMA

doi:10.1271/bbb.64.417

Biochemistry & Molecular Biology Notes

Effect of a Polysaccharide (TAP) from the Fruiting Bodies of Tremella aurantia on Glucose Metabolism in Mouse Liver

Tadashi KIHO, Hotaka MORIMOTO, Takashi KOBAYASHI, Shigeyuki USUI, Shigeo UKAI, Koichi AIZAWA, Takahiro INAKUMA

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Keywords: Tremella aurantia, polysaccharide, glucokinase, glucose-6-phosphatase, cholesterol

JOURNAL FREE ACCESS

2000 Volume 64 Issue 2 Pages 417-419

DOI https://doi.org/10.1271/bbb.64.417

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Abstract

An acidic polysaccharide (TAP) obtained from the fruiting bodies of Tremella aurantia significantly increased the activities of glucokinase, hexokinase, and glucose-6-phosphate dehydrogenase, and decreased the activity of glucose-6-phosphatase in normal and diabetic mouse liver after intraperitoneal administration, while the glycogen content in the liver was reduced. Furthermore, TAP lowered the plasma cholesterol level in normal and diabetic mice.

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