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Bioscience, Biotechnology, and Biochemistry
Vol. 64 (2000) No. 3 P 670-673



Biochemistry & Molecular Biology Preliminary Communication

  We developed a semi-automated genome analysis system called GAMBLER in order to support the current whole-genome sequencing project focusing on alkaliphilic Bacillus halodurans C-125. GAMBLER was designed to reduce the human intervention required and to reduce the complications in annotating thousands of ORFs in the microbial genome. GAMBLER automates three major routines: analyzing assembly results provided by genome assembler software, assigning ORFs, and homology searching. GAMBLER is equipped with an interface for convenience of annotation. All processes and options are manipulatable through a WWW browser that enables scientists to share their genome analysis results without choosing computer platforms.

Copyright © 2000 by Japan Society for Bioscience, Biotechnology, and Agrochemistry

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