Paeonilide, a Novel Anti-PAF-active Monoterpenoid-derived Metabolite from Paeonia delavayi

LIU Ji-Kai; MA Yun-Bao; WU Da-Gang; LU Yang; SHEN Zhi-Qiang; ZHENG Qi-Tai; CHEN Zhi-He

doi:10.1271/bbb.64.1511

Bioscience, Biotechnology, and Biochemistry

Online ISSN : 1347-6947
Print ISSN : 0916-8451

Organic Chemistry Notes

Paeonilide, a Novel Anti-PAF-active Monoterpenoid-derived Metabolite from Paeonia delavayi

LIU Ji-Kai, MA Yun-Bao, WU Da-Gang, LU Yang, SHEN Zhi-Qiang, ZHENG Qi-Tai, CHEN Zhi-He

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Keywords: paeonilide, monoterpenoid, anti-PAF, Paeonia delavayi

JOURNAL FREE ACCESS

2000 Volume 64 Issue 7 Pages 1511-1514

DOI https://doi.org/10.1271/bbb.64.1511

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Abstract

A novel monoterpenoid-derived metabolite, paeonilide, was isolated from the roots of Paeonia delavayi. Its structure was established by a combination of spectroscopic and X-ray crystallographic analyses. It showed an anti-PAF effect with an IC₅₀ value of ca. 8 μg/ml.

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