Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Food & Nutrition Science Notes
Suppression of D-Galactosamine-induced Liver Injury by Mushrooms in Rats
Eun Woo LEEPuming HEHirokazu KAWAGISHIKimio SUGIYAMA
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2000 年 64 巻 9 号 p. 2001-2004

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  Six species of edible mushroom were found to suppress D-galactosamine-induced enhancement of plasma alanine and aspartate aminotransferase activities when powdered mushrooms were added to the diet (5%) and fed to rats for 2 wk. Grifola frondosa exhibited the most potent effect in a dose-dependent manner. A significant effect was observed only from the water-soluble low-molecular-weight fraction of G. frondosa. The results indicate that several mushrooms possess a protective effect against liver injury induced by D-galactosamine.
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© 2000 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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