Analysis of the Isoform of Xenopus Euakryotic Translation Initiation Factor 4E

Motoaki WAKIYAMA; Aki SUZUKI; Motoki SAIGOH; Nobuya SAKAI; Hiroshi MIYOSHI; Shuichi KOJIMA; Kin-ichiro MIURA

doi:10.1271/bbb.65.232

Bioscience, Biotechnology, and Biochemistry

Online ISSN : 1347-6947
Print ISSN : 0916-8451

Biochemistry & Molecular Biology

Analysis of the Isoform of Xenopus Euakryotic Translation Initiation Factor 4E

Motoaki WAKIYAMA, Aki SUZUKI, Motoki SAIGOH, Nobuya SAKAI, Hiroshi MIYOSHI, Shuichi KOJIMA, Kin-ichiro MIURA

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Keywords: translation initiation factor 4E, isoform, Xenopus

JOURNAL FREE ACCESS

2001 Volume 65 Issue 1 Pages 232-235

DOI https://doi.org/10.1271/bbb.65.232

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Abstract

We have found two isoforms of the eukaryotic translation initiation factor 4E (eIF4E) in Xenopus laevis. These proteins differ in length by 18 amino acids. Overexpression of either of the two eIF4E proteins modestly increase translation in Xenopus oocytes. The results suggest that both of these two isoforms function in translation.

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