First Stereoselective Synthesis of (+)-Magnostellin C, a Tetrahydrofuran Type of Lignan Bearing a Chiral Secondary Benzyl Alcohol

Abstract

(+)-Magnostellin C, which is a tetrahydrofuran type of lignan bearing a chiral secondary benzylic hydroxy group, was stereoselectively synthesized from L-arabinose by using threo selective aldol condensation.