Isolation and Structure Elucidation of a New Antifungal and Antibacterial Antibiotic Produced by Streptomyces sp. 201

Gajen N. BORDOLOI; Babita KUMARI; Arijit GUHA; Manobjyoti BORDOLOI; R.N.S. YADAV; Monoj K. ROY; Tarun C. BORA

doi:10.1271/bbb.65.1856

Organic Chemistry

Isolation and Structure Elucidation of a New Antifungal and Antibacterial Antibiotic Produced by Streptomyces sp. 201

Gajen N. BORDOLOI, Babita KUMARI, Arijit GUHA, Manobjyoti BORDOLOI, R.N.S. YADAV, Monoj K. ROY, Tarun C. BORA

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Keywords: Streptomyces sp. 201, antibacterial, antifungal, antibiotic, 2-methylheptyl isonicotinate

JOURNAL FREE ACCESS

2001 Volume 65 Issue 8 Pages 1856-1858

DOI https://doi.org/10.1271/bbb.65.1856

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Abstract

An antibacterial and antifungal antibiotic was isolated from the culture filtrate of Streptomyces sp. 201, and its structure was determined as 2-methyl-heptyl isonicotinate by extensive use of NMR spectroscopy. The compound exhibited marked antimicrobial activity against Bacillus subtilis, Shigella sp., Klebsiella sp., E. coli, Proteus mirabilis, and the pathogenic fungi, Fusarium moniliforme, F. semitectum, F. oxysporum, F. solani and Rhizoctonia solani.

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