2002 Volume 66 Issue 3 Pages 636-640
Animal sera were screened for an alternative enzyme source of α1,3-fucosyltransferase, and the highest activity was observed in chicken serum. A partially purified enzyme fraction almost devoid of coexisting glycosidases was prepared from the chicken serum, and used for the fucosylation of LacNAc compounds. The enzyme reaction was efficient enough to allow the one-pot preparation of designed Lex compounds such as LNFP III.
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