Myrsinoic Acids B, C and F, Anti-inflammatory Compounds from Myrsine seguinii

Mitsuru HIROTA; Shintaro MIYAZAKI; Tomomi MINAKUCHI; Tomoko TAKAGI; Hisao SHIBATA

doi:10.1271/bbb.66.655

Bioscience, Biotechnology, and Biochemistry

Online ISSN : 1347-6947
Print ISSN : 0916-8451

Organic Chemistry Notes

Myrsinoic Acids B, C and F, Anti-inflammatory Compounds from Myrsine seguinii

Mitsuru HIROTA, Shintaro MIYAZAKI, Tomomi MINAKUCHI, Tomoko TAKAGI, Hisao SHIBATA

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Keywords: Myrsine seguinii, anti-inflammatory, TPA-induced edema

JOURNAL FREE ACCESS

2002 Volume 66 Issue 3 Pages 655-659

DOI https://doi.org/10.1271/bbb.66.655

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Abstract

The methanolic extract of Myrsine seguinii yielded three anti-inflammatory compounds, myrsinoic acids B, C and F, and their structures were elucidated from the spectroscopic data. These compounds suppressed the TPA-induced edema of mouse ear, myrsinoic acid F being the most active (IE 77% at a dose of 0.56 μmol).

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