5-Bromo-2′-deoxyuridine Efficiently Suppresses Division Potential of the Yeast Saccharomyces cerevisiae

Michihiko FUJII; Hisasi ITO; Tsutomu HASEGAWA; Toshikazu SUZUKI; Noritaka ADACHI; Dai AYUSAWA

doi:10.1271/bbb.66.906

Bioscience, Biotechnology, and Biochemistry

Online ISSN : 1347-6947
Print ISSN : 0916-8451

Biochemistry & Molecular Biology Notes

5-Bromo-2′-deoxyuridine Efficiently Suppresses Division Potential of the Yeast Saccharomyces cerevisiae

Michihiko FUJII, Hisasi ITO, Tsutomu HASEGAWA, Toshikazu SUZUKI, Noritaka ADACHI, Dai AYUSAWA

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Keywords: yeast, thymidine auxotroph, 5-bromo-2′-deoxyuridine, growth, senescence

JOURNAL FREE ACCESS

2002 Volume 66 Issue 4 Pages 906-909

DOI https://doi.org/10.1271/bbb.66.906

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Abstract

We established a thymidine-auxotrophic strain of the yeast Saccharomyces cerevisiae to examine biological effects of thymidine analogues. 5-Bromo-2′-deoxyuridine efficiently suppressed the division potential of yeast showing morphology similar to senescent cells.

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