Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Organic Chemistry Notes
Prevention by Polyhydroxysteroids and Saponins of Asterina pectinifera of the Desquamation of Stratum Corneum Cells
Kazuyo UKAIAtsufumi IWANAGAHiroshi NAGAIMichio NAMIKOSHI
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JOURNAL FREE ACCESS

2002 Volume 66 Issue 4 Pages 913-915

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Abstract

  Two polyhydroxysteroids and three steroidal saponins (pectiniosides A, B and C) were isolated as bioactive substances from Asterina pectinifera. These compounds inhibited the release of guinea-pig skin stratum corneum cells by 48–67% (control, 0%) at 2 mg/ml. It is suggested that the bioactivity of these compounds is connected with the remedial and preventive effects of an aqueous extract of A. pectinifera on rough human skin.

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© 2002 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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