Prevention by Polyhydroxysteroids and Saponins of Asterina pectinifera of the Desquamation of Stratum Corneum Cells

Kazuyo UKAI; Atsufumi IWANAGA; Hiroshi NAGAI; Michio NAMIKOSHI

doi:10.1271/bbb.66.913

Organic Chemistry Notes

Prevention by Polyhydroxysteroids and Saponins of Asterina pectinifera of the Desquamation of Stratum Corneum Cells

Kazuyo UKAI, Atsufumi IWANAGA, Hiroshi NAGAI, Michio NAMIKOSHI

著者情報

キーワード: Asterina pectinifera, polyhydroxysteroid, steroidal saponin, desquamation, stratum corneum

ジャーナルフリー

2002 年 66 巻 4 号 p. 913-915

DOI https://doi.org/10.1271/bbb.66.913

詳細

抄録

Two polyhydroxysteroids and three steroidal saponins (pectiniosides A, B and C) were isolated as bioactive substances from Asterina pectinifera. These compounds inhibited the release of guinea-pig skin stratum corneum cells by 48–67% (control, 0%) at 2 mg/ml. It is suggested that the bioactivity of these compounds is connected with the remedial and preventive effects of an aqueous extract of A. pectinifera on rough human skin.

責任著者(Corresponding author)

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