Effects of Oxygenated Carotenoid β-Cryptoxanthin on Morphological Differentiation and Apoptosis in Neuro2a Neuroblastoma Cells

Satoko NOGUCHI; Takashi SUMIDA; Hiroshi OGAWA; Mikiro TADA; Kyoya TAKAHATA

doi:10.1271/bbb.67.2467

Food & Nutrition Science Notes

Effects of Oxygenated Carotenoid β-Cryptoxanthin on Morphological Differentiation and Apoptosis in Neuro2a Neuroblastoma Cells

Satoko NOGUCHI, Takashi SUMIDA, Hiroshi OGAWA, Mikiro TADA, Kyoya TAKAHATA

著者情報

キーワード: β-cryptoxanthin, Neuro2a cells, neurite, caspase-3, apoptosis

ジャーナルフリー

2003 年 67 巻 11 号 p. 2467-2469

DOI https://doi.org/10.1271/bbb.67.2467

詳細

抄録

Beta-Cryptoxanthin (βCx) was investigated for cell functions in neuroblastoma Neuro2a cells. The following results were obtained. 1. Beta-Cx induced neurite outgrowth. 2. Beta-Cx inhibited the etoposide-induced activation of caspase-3 activity in a dose-dependent manner. These data suggest a bioregulatry function of βCx in the control of differentiation and apoptosis in Neuro2a cells.

責任著者(Corresponding author)

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