Synthesis of All Four Stereoisomers of 3-Amino-2-hydroxybutanoic Acids

Jin Hwan LEE; Min Suk YANG; Kuy Young KANG; Yea Hwang MOON; Ki Hun PARK

doi:10.1271/bbb.68.714

Bioscience, Biotechnology, and Biochemistry

Online ISSN : 1347-6947
Print ISSN : 0916-8451

Organic Chemistry Regular Papers

Synthesis of All Four Stereoisomers of 3-Amino-2-hydroxybutanoic Acids

Jin Hwan LEE, Min Suk YANG, Kuy Young KANG, Yea Hwang MOON, Ki Hun PARK

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Keywords: isothreonine, alloisothreonine, simultaneous dealkoxyhalogenation, D-gulonic acid γ-lactone, D-glucono-δ-lactone

JOURNAL FREE ACCESS

2004 Volume 68 Issue 3 Pages 714-720

DOI https://doi.org/10.1271/bbb.68.714

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Abstract

All four stereoisomers of 3-amino-2-hydroxybutanoic acids were been obtained as single enantiomers via stereospecific reactions from D-gulonic acid γ-lactone and D-glucono-δ-lactone.

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