Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Organic Chemistry Note
Prolyl Endopeptidase and Thrombin Inhibitory Diterpenoids from the Bark of Xylopia aethiopica
Noungoue Tchamo DIDEROTNgouela SILVEREAmsha YASINSeema ZAREENZelefack FABIENTsamo ETIENNEM. Iqbal CHOUDHARYATTA-UR-RAHMAN
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2005 年 69 巻 9 号 p. 1763-1766

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The inhibitory effects of seven diterpenes, belonging to three different structural classes and isolated from the bark of Xylopia aethiopica, were investigated against the enzymes prolyl endopeptidase (PEP) and α-thrombin. Five compounds exhibited inhibitory activity against them.
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© 2005 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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