Degradation of PrPSc by Keratinolytic Protease from Nocardiopsis sp. TOA-1

Shinji MITSUIKI; Zhao HUI; Daishi MATSUMOTO; Masashi SAKAI; Yasushi MORIYAMA; Kensuke FURUKAWA; Hiroaki KANOUCHI; Tatsuzo OKA

doi:10.1271/bbb.70.1246

Bioscience, Biotechnology, and Biochemistry

Online ISSN : 1347-6947
Print ISSN : 0916-8451

Biochemistry & Molecular Biology Notes

Degradation of PrP^Sc by Keratinolytic Protease from Nocardiopsis sp. TOA-1

Shinji MITSUIKI, Zhao HUI, Daishi MATSUMOTO, Masashi SAKAI, Yasushi MORIYAMA, Kensuke FURUKAWA, Hiroaki KANOUCHI, Tatsuzo OKA

著者情報

キーワード: prion, alkaline protease, keratinase, Nocardiopsis sp.

ジャーナルフリー

2006 年 70 巻 5 号 p. 1246-1248

DOI https://doi.org/10.1271/bbb.70.1246

詳細

抄録

A keratinolytic alkaline proteae (NAPase) from Nocardiopsis sp. TOA-1 degraded a scrapie prion without any chemical or physical treatment. Optimal temperature and pH were 60 °C and above pH 10.0. The scrapie prion was completely degraded within 3 min under optimal conditions.

著者関連情報

この記事は最新の被引用情報を取得できません。

お気に入り & アラート

前身誌

Bulletin of the Agricultural Chemical Society of Japan

Agricultural and Biological Chemistry

feedback

Top

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）