Oral Administration of a Heat-Killed Cell Preparation of Enterococcus faecalis Strain EC-12 Stimulates the Gene Expression of Na+–K+–2Cl− Co-Transporter 1 in Rat Ileal Epithelial Cells

Ryo INOUE; Takamitsu TSUKAHARA; Mamiko NODA; Wakoto BUKAWA; Noritaka MATSUBARA; Kazunari USHIDA

doi:10.1271/bbb.60589

Food & Nutrition Science Notes

Oral Administration of a Heat-Killed Cell Preparation of Enterococcus faecalis Strain EC-12 Stimulates the Gene Expression of Na⁺–K⁺–2Cl⁻ Co-Transporter 1 in Rat Ileal Epithelial Cells

Ryo INOUE, Takamitsu TSUKAHARA, Mamiko NODA, Wakoto BUKAWA, Noritaka MATSUBARA, Kazunari USHIDA

著者情報

キーワード: heat-killed bacteria, Na⁺–K⁺–2Cl⁻ co-transporter 1, RT-PCR, rat

ジャーナルフリー

2007 年 71 巻 3 号 p. 807-810

DOI https://doi.org/10.1271/bbb.60589

View "Advance Publication" version (March 7, 2007).

詳細

抄録

The effect of a heat-killed cell preparation of Enterococcus faecalis strain EC-12 (EC-12) on the gene expression of Na⁺–K⁺–2Cl⁻ co-transporter 1 (NKCC1) in intestinal epithelial cells was evaluated by using rats. The NKCC1 gene in ileal epithelial cells was significantly up-regulated by the oral administration of EC-12. The results of this study suggest in vivo that EC-12 had the potential to stimulate intestinal NKCC1 expression.

責任著者(Corresponding author)

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