Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Food & Nutrition Science Notes
Improvement of the Antitumor Activity of Black Currant Polysaccharide by an Enzymatic Treatment
Ryoji TAKATATakaaki YANAIReiko YAMAMOTOTomonori KONNO
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2007 年 71 巻 5 号 p. 1342-1344

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A polysaccharide-rich substance isolated from black currant, named cassis polysaccharide (CAPS), was partially digested with β-galactosidase from Aspergillus oryzae and its immunostimulatory activity was investigated. The in vitro cytokine-inducing effect of CAPS on RAW264 cells was gradually decreased along with lowering of the average MW of CAPS. In vivo, partially digested CAPS with a mean MW of approximately 20,000 showed the most potent antitumor activity against Ehrlich carcinoma in mice.
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© 2007 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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