Biosynthesis of Castor Oil: Effect of Polyamines on the Acylation of Lysophosphatidic Acid at the sn-2 Position with Ricinoleic Acid

Mitsuhiro TOMOSUGI; Akane OHSHIRO; Shin’ichiro HARA; Ken’ichi ICHIHARA

doi:10.1271/bbb.70044

Biochemistry & Molecular Biology Notes

Biosynthesis of Castor Oil: Effect of Polyamines on the Acylation of Lysophosphatidic Acid at the sn-2 Position with Ricinoleic Acid

Mitsuhiro TOMOSUGI, Akane OHSHIRO, Shin’ichiro HARA, Ken’ichi ICHIHARA

著者情報

キーワード: polyamine, lysophosphatidic acid acyltransferase, 2-ricinoleoyl phosphatidic acid

ジャーナルフリー

2007 年 71 巻 8 号 p. 2052-2056

DOI https://doi.org/10.1271/bbb.70044

View "Advance Publication" version (August 7, 2007).

詳細

抄録

Polyamines with diamine structures of chain length longer than 3C were essential for the synthesis of phosphatidic acid (PA) from ricinoleoyl-CoA and lysophosphatidic acid (LPA) by the castor LPA acyltransferase reaction, suggesting that polyamines modulate enzyme affinity for the acyl-CoA substrate in vivo.

責任著者(Corresponding author)

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