Expression of the Ha-ras Suppressor Family Member 5 Gene in the Maturing Rat Testis

Yoshiaki YAMANO; Atsushi ASANO; Kenji OHYAMA; Masanori OHTA; Ren NISHIO; Isao MORISHIMA

doi:10.1271/bbb.70673

Biochemistry & Molecular Biology Notes

Expression of the Ha-ras Suppressor Family Member 5 Gene in the Maturing Rat Testis

Yoshiaki YAMANO, Atsushi ASANO, Kenji OHYAMA, Masanori OHTA, Ren NISHIO, Isao MORISHIMA

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Keywords: Hrasls5, in situ hybridization, RLP-1, spermatogenesis, tumor suppressor

JOURNAL FREE ACCESS

2008 Volume 72 Issue 5 Pages 1360-1363

DOI https://doi.org/10.1271/bbb.70673

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Abstract

We analyzed the gene expression of Ha-ras suppressor family member 5 (Hrasls5), which is considered to modulate the Ha-ras signaling cascade, from maturing rat testis. Expression was detected primarily in the spermatocytes in the maturing rat testis. The Hrasls5 gene product might function as a tumor suppressor as well as in spermatogenesis, as deduced from its amino acid sequence.

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