Food & Nutrition Science Notes
Hypoglycemic Effect of 13-Membered Ring Thiocyclitol, a Novel α-Glucosidase Inhibitor from Kothala-himbutu (Salacia reticulata)
2008 年 72 巻 7 号 p. 1962-1964
詳細
2008 年 72 巻 7 号 p. 1962-1964
A novel 13-membered ring thiocyclitol, isolated from an aqueous extract of Kothala-himbutu (Salacia reticulata), inhibited α-glucosidase in vitro. The inhibitory activity was investigated by maltose- and sucrose-loading on Wistar rats. This study found significant lowering of postprandial glucose levels, and the potency of 13-membered ring thiocyclitol was confirmed in vivo.
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