Different Suppressive Effects of Fucoidan and Lentinan on IL-8 mRNA Expression in in Vitro Gut Inflammation

Masashi MIZUNO; Yosuke NISHITANI; Takashi HASHIMOTO; Kazuki KANAZAWA

doi:10.1271/bbb.90326

Food & Nutrition Science Notes

Different Suppressive Effects of Fucoidan and Lentinan on IL-8 mRNA Expression in in Vitro Gut Inflammation

Masashi MIZUNO, Yosuke NISHITANI, Takashi HASHIMOTO, Kazuki KANAZAWA

著者情報

キーワード: fucoidan, lentinan, interleukin-8, tumor necrosis factor-α, intestinal bowel diseases

ジャーナルフリー

2009 年 73 巻 10 号 p. 2324-2325

DOI https://doi.org/10.1271/bbb.90326

View "Advance Publication" version (October 7, 2009).

詳細

抄録

A system for assessing the anti-inflammatory effects of food factors was developed by establishing a co-culture system with intestinal epithelial Caco-2 cells and macrophage RAW264.7 cells. The results indicate that fucoidan and lentinan exhibited different suppressive effects on interleukin-8 (IL-8) mRNA expression in Caco-2 through tumor necrosis factor-α (TNF-α) production from RAW264.7 stimulated with lipopolysaccharide (LPS).

責任著者(Corresponding author)

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