Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Food & Nutrition Science Regular Papers
Effects of Oral Supplementation with Cystine and Theanine on the Immune Function of Athletes in Endurance Exercise: Randomized, Double-Blind, Placebo-Controlled Trial
Shigeki MURAKAMIShigekazu KURIHARANatsue KOIKAWAAkira NAKAMURAKazuhiro AOKIHiroshi YOSIGIKeisuke SAWAKIMasaru OHTANI
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2009 Volume 73 Issue 4 Pages 817-821

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Abstract

Athletes become increasingly susceptible to infection with intense training that results in immune suppression. The immune state was investigated after administering cystine/theanine (CT), which has been reported to have an immune reinforcement effect, to athletes before training involving a prolonged period of intense exercise. Fifteen long-distance runners were each allocated to the CT or placebo group, and the test food was ingested for 10 d prior to the start of training. Clinical examinations were performed before and after the training. The results indicate a significant increase in the high-sensitivity C-reactive protein (hs-CRP) and neutrophil count in the blood, as well as a decreasing tendency for lymphocytes in the placebo group, but not the CT group. These observations suggest that the ingestion of CT contributed to suppressing the change in inflammatory response, prevented a decrease in the immune function, and prevented infection and reduced symptoms when infected associated with continuous intense exercise.

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© 2009 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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