Physiological Effects of Dietary PIPS Soybean-Derived Phospholipid in Obese Zucker (fa/fa) Rats

Bungo SHIROUCHI; Koji NAGAO; Kenta FURUYA; Masatoshi SHIOJIRI; Xiaoli LIU; Teruyoshi YANAGITA

doi:10.1271/bbb.100408

Food & Nutrition Science Notes

Physiological Effects of Dietary PIPS Soybean-Derived Phospholipid in Obese Zucker (fa/fa) Rats

Bungo SHIROUCHI, Koji NAGAO, Kenta FURUYA, Masatoshi SHIOJIRI, Xiaoli LIU, Teruyoshi YANAGITA

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Keywords: phosphatidylinositol, phosphatidylserine, fatty liver, Zucker (fa/fa) rat

JOURNAL FREE ACCESS

2010 Volume 74 Issue 11 Pages 2333-2335

DOI https://doi.org/10.1271/bbb.100408

View "Advance Publication" version (November 7, 2010).

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Abstract

The effects of soybean-derived phospholipid, PIPS NAGASE^TM (PIPS), on obesity-induced diseases were studied in obese rats. Dietary PIPS alleviated hepatomegaly and fatty liver in the rats. These effects were attributable to reduced lipogenesis and enhanced lipolysis in the liver. The results suggest that PIPS can be useful as a dietary component that would reduce the risk of lifestyle-related diseases.

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