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Bioscience, Biotechnology, and Biochemistry
Vol. 75 (2011) No. 10 P 2066-2069

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http://doi.org/10.1271/bbb.110459

Biochemistry & Molecular Biology Notes

Fucoxanthin is a non-provitamin A carotenoid contained in brown seaweeds. We found that it suppressed interleukin-17 secretion from CD4+ T cells under IL-17-producing T (Th17) cell development conditions. By evaluating T cell differentiation in vitro, fucoxanthin and its metabolite fucoxanthinol inhibited T cell differentiation into Th17 cells. This suggests that fucoxanthin can improve inflammatory diseases due to Th17 cells.

Copyright © 2011 by Japan Society for Bioscience, Biotechnology, and Agrochemistry

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