The Level of Orally Ingested Vitamin C Affected the Expression of Vitamin C Transporters and Vitamin C Accumulation in the Livers of ODS Rats

Yasuko SONE; Etsuko UETA; Satoru KODAMA; Yasuko SANNOUMARU; Noriko MIYAKE; Hirohito SONE; Yoko FUJIWARA; Yuzuru OTSUKA; Kazuo KONDO; Masahiro INAGAKI; Eiji NAMBA; Tadao KURATA; Emiko SUZUKI

doi:10.1271/bbb.110312

Food & Nutrition Science Notes

The Level of Orally Ingested Vitamin C Affected the Expression of Vitamin C Transporters and Vitamin C Accumulation in the Livers of ODS Rats

Yasuko SONE, Etsuko UETA, Satoru KODAMA, Yasuko SANNOUMARU, Noriko MIYAKE, Hirohito SONE, Yoko FUJIWARA, Yuzuru OTSUKA, Kazuo KONDO, Masahiro INAGAKI, Eiji NAMBA, Tadao KURATA, Emiko SUZUKI

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Keywords: 2-O-α-D-glucopyranosyl-L-ascorbic acid, L-ascorbic acid, ODS/ShiJcl-od/od (ODS) rat, sodium-dependent vitamin C transporter

JOURNAL FREE ACCESS

2011 Volume 75 Issue 12 Pages 2394-2397

DOI https://doi.org/10.1271/bbb.110312

View "Advance Publication" version (December 7, 2011).

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Abstract

We investigated the effects of vitamin C administration on vitamin C-specific transporters in ODS/ShiJcl-od/od rat livers. The vitamin C-specific transporter levels increased in the livers of the rats not administered vitamin C and decreased in the livers of those administered vitamin C at 100 mg/d, indicating that these transporter levels can be influenced by the amount of vitamin C administered.

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