A New Pathway for Poly(3-hydroxybutyrate) Production in Escherichia coli and Corynebacterium glutamicum by Functional Expression of a New Acetoacetyl-coenzyme A Synthase

Ken’ichiro MATSUMOTO; Miwa YAMADA; Chean Ring LEONG; Sung-Jin JO; Tomohisa KUZUYAMA; Seiichi TAGUCHI

doi:10.1271/bbb.100682

Microbiology & Fermentation Technology Notes

A New Pathway for Poly(3-hydroxybutyrate) Production in Escherichia coli and Corynebacterium glutamicum by Functional Expression of a New Acetoacetyl-coenzyme A Synthase

Ken’ichiro MATSUMOTO, Miwa YAMADA, Chean Ring LEONG, Sung-Jin JO, Tomohisa KUZUYAMA, Seiichi TAGUCHI

著者情報

キーワード: acetoacetyl-coenzyme A (CoA) synthesizing enzyme, acetyl-CoA, biodegradable plastics, biopolyester, malonyl-CoA

ジャーナルフリー

2011 年 75 巻 2 号 p. 364-366

DOI https://doi.org/10.1271/bbb.100682

View "Advance Publication" version (February 7, 2011).

詳細

抄録

A biosynthetic pathway for poly(3-hydroxybutyrate) [P(3HB)] was developed in Escherichia coli and Corynebacterium glutamicum by an acetoacetyl-coenzyme A (CoA) synthase (AACS) recently isolated from terpenoid-producing Streptomyces sp. strain CL190. Expression of AACS led to significant productions of P(3HB) in E. coli (10.5 wt %) and C. glutamicum (19.7 wt %).

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）