Comparison of the Efficacy of Alpha-Lactalbumin from Equine, Bovine, and Human Milk in the Growth of Intestinal IEC-6 Cells

XIJIER; Yuki MORI; Mayuko FUKUOKA; CAIRANGZHUOMA; Mizuho INAGAKI; Satoshi IWAMOTO; Tomio YABE; Yoshihiro KANAMARU

doi:10.1271/bbb.110896

Food & Nutrition Science Notes

Comparison of the Efficacy of Alpha-Lactalbumin from Equine, Bovine, and Human Milk in the Growth of Intestinal IEC-6 Cells

XIJIER, Yuki MORI, Mayuko FUKUOKA, CAIRANGZHUOMA, Mizuho INAGAKI, Satoshi IWAMOTO, Tomio YABE, Yoshihiro KANAMARU

著者情報

キーワード: α-lactalbumin, 2,2,2-trifluoroethanol, IEC-6 cells, cell death

ジャーナルフリー

2012 年 76 巻 4 号 p. 843-846

DOI https://doi.org/10.1271/bbb.110896

View "Advance Publication" version (April 7, 2012).

詳細

抄録

Native alpha-lactalbumins (α-LA) from equine, bovine, and human milk were not cytotoxic. However, after treatment with trifluoroethanol (TFE), all three α-LAs exhibited cytotoxicity. Toxic potencies were distinctly different among them. Equine α-LA was the most robust, bovine α-LA was moderate, and human α-LA was weak. There were no significant structural changes as between the native and the TFE-treated α-LAs.

責任著者(Corresponding author)

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