Identification of Enterocin NKR-5-3C, a Novel Class IIa Bacteriocin Produced by a Multiple Bacteriocin Producer, Enterococcus faecium NKR-5-3

Kohei HIMENO; Koji FUJITA; Takeshi ZENDO; Pongtep WILAIPUN; Naoki ISHIBASHI; Yoshimitsu MASUDA; Fuminori YONEYAMA; Vichien LEELAWATCHARAMAS; Jiro NAKAYAMA; Kenji SONOMOTO

doi:10.1271/bbb.120089

Microbiology & Fermentation Technology Note

Identification of Enterocin NKR-5-3C, a Novel Class IIa Bacteriocin Produced by a Multiple Bacteriocin Producer, Enterococcus faecium NKR-5-3

Kohei HIMENO, Koji FUJITA, Takeshi ZENDO, Pongtep WILAIPUN, Naoki ISHIBASHI, Yoshimitsu MASUDA, Fuminori YONEYAMA, Vichien LEELAWATCHARAMAS, Jiro NAKAYAMA, Kenji SONOMOTO

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Keywords: bacteriocin, lactic acid bacteria, Enterococcus faecium, enterocin, pediocin

JOURNAL FREE ACCESS

2012 Volume 76 Issue 6 Pages 1245-1247

DOI https://doi.org/10.1271/bbb.120089

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Abstract

The structure of enterocin NKR-5-3C, an anti-listerial bacteriocin produced by a multiple bacteriocin producer, Enterococcus faecium NKR-5-3, was determined. Enterocin NKR-5-3C is a novel class IIa bacteriocin that possesses an YGNGL motif sequence and two disulfide bridges in its structure. It is encoded on gene ent53C together with an 18-amino-acid-residue double glycine leader peptide.

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