Synthesis of Bioactive Natural Products as Protein Inhibitors

Hiroyuki KONNO

doi:10.1271/bbb.120176

Bioscience, Biotechnology, and Biochemistry

Online ISSN : 1347-6947
Print ISSN : 0916-8451

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Synthesis of Bioactive Natural Products as Protein Inhibitors

Hiroyuki KONNO

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Keywords: unusual amino acid, peptidyl natural product, marine sponge, cysteine protease inhibitor, SARS-CoV

JOURNAL FREE ACCESS

2012 Volume 76 Issue 7 Pages 1257-1261

DOI https://doi.org/10.1271/bbb.120176

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Abstract

Synthetic studies of Annonaceous acetogenins isolated from the plant family Annonaceae and marine natural products (miraziridine A, tokaramide A, and callipeltins) containing unusual amino acids, and recent studies of the structure-activity relationship of cysteine protease inhibitor are described.

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