New Chrodrimanin Congeners, Chrodrimanins D–H, from YO-2 of Talaromyces sp.

Abstract

Four new meroterpenoids, named chrodrimanins D–G (4–7), and one known compound, renamed chrodrimanin H (8), were isolated from okara (the insoluble residue of whole soybean) that had been fermented with the YO-2 strain of Talaromyces sp. Their structures were elucidated by spectroscopic methods. Chrodrimanins D (4), E (5), and F (6) showed insecticidal activity against silkworms with respective LD₅₀ values of 20, 10, and 50 µg/g of diet.