2013 Volume 77 Issue 6 Pages 1303-1305
Sparassis crispa (SC) contains significant concentrations of β-glucan, which can accelerate wound healing, but the dose dependence for oral administration and the effects of topical administration are unknown. In streptozotocin-induced diabetic mice, dietary SC promoted dose-dependent effective wound healing. Similar wound healing activity was observed when purified SC β-glucan was topically applied to wounds of diabetic mice.
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