Differential Substrate Specificity of Two Inositol Transporters of Bacillus subtilis

Tetsuro MORINAGA; Takatsugu MATSUSE; Hitoshi ASHIDA; Ken-ichi YOSHIDA

doi:10.1271/bbb.100125

This article has now been updated. Please use the final version.

Differential Substrate Specificity of Two Inositol Transporters of Bacillus subtilis

Tetsuro MORINAGA, Takatsugu MATSUSE, Hitoshi ASHIDA, Ken-ichi YOSHIDA

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Keywords: myo-inositol, D-chiro-inositol, Bacillus subtilis, transporter

JOURNAL FREE ACCESS Advance online publication

Article ID: 100125

DOI https://doi.org/10.1271/bbb.100125

The final version of this article is now available: Vol. 74 (2010) , No. 6 p.1312

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Abstract

Bacillus subtilis IolT is the major myo-inositol transporter for growth, while IolF is a minor one unable to support growth. We found that either IolT or IolF was sufficient for moderate growth using D-chiro-inositol. Conversely to IolT, IolF transported D-chiro-inositol more preferentially than myo-inositol. These results indicate that IolT and IolF are different in substrate specificity.

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